Medical decision making on behalf of unrepresented patients is one of the most challenging ethical issues faced in clinical practice. The legal environment surrounding these patients is equally complex. This article describes the efforts of a small coalition of interested healthcare professionals to address the issue in Colorado. A brief history of the effort is presented, along with discussion of the legal, ethical, practical, and political dimensions that arose in Colorado’s effort to address decision making for unrepresented patients through an (...) extension of the existing Colorado Medical Treatment Decision Act (CRS 15-18). A discussion of lessons learned in the process is included. (shrink)

Risk management of nanotechnology is challenged by the enormous uncertainties about the risks, benefits, properties, and future direction of nanotechnology applications. Because of these uncertainties, traditional risk management principles such as acceptable risk, cost–benefit analysis, and feasibility are unworkable, as is the newest risk management principle, the precautionary principle. Yet, simply waiting for these uncertainties to be resolved before undertaking risk management efforts would not be prudent, in part because of the growing public concerns about nanotechnology driven by risk perception (...) heuristics such as affect and availability. A more reflexive, incremental, and cooperative risk management approach is required, which not only will help manage emerging risks from nanotechnology applications, but will also create a new risk management model for managing future emerging technologies. (shrink)

As policy makers struggle to develop regulatory oversight models for nanotechnologies, there are important lessons that can be drawn from previous attempts to govern other emerging technologies. Five such lessons are the following: public confidence and trust in a technology and its regulatory oversight is probably the most important factor for the commercial success of a technology; regulation should avoid discriminating against particular technologies unless there is a scientifically based rationale for the disparate treatment; regulatory systems need to be flexible (...) and adaptive to rapidly changing technologies; ethical and social concerns of the public about emerging technologies need to be expressly acknowledged and addressed in regulatory oversight; and international harmonization of regulation may be beneficial in a rapidly globalizing world. (shrink)

Nanotechnology is the latest in a growing list of emerging technologies that includes nuclear technologies, genetics, reproductive biology, biotechnology, information technology, robotics, communication technologies, surveillance technologies, synthetic biology, and neuroscience. As was the case for many of the technologies that came before, a key question facing nanotechnology is what type of regulatory oversight is appropriate for this emerging technology. As two of us wrote several years ago, the question facing nanotechnology is not whether it will be regulated, but when and (...) how.Yet, appropriate regulation of nanotechnology will be challenging. The term “nanotechnology” incorporates a broad, diverse range of materials, technologies, and products, with an even greater spectrum of potential risks and benefits. This technology slashes across the jurisdiction of many existing regulatory statutes and regulatory agencies, and does so across the globe. Nanotechnology is developing at an enormously rapid rate, perhaps surpassing the capability of any potential regulatory framework to keep pace. Finally, the risks of nanotechnology remain largely unknown, both because of the multitude of variations in the technology and because of the limited applicability of traditional toxicological approaches such as structure-activity relationship to nanotechnology products. (shrink)

The Many Faces of Patriotism debate the consequences of the 21st century's patriotic resurgence, examining it both in theoretical and comparative terms that draw on examples of patriotism from ancient Greece to post-apartheid South Africa.

Orthologic is defined by weakening the axioms and rules of inference of the classical propositional calculus. The resulting Lindenbaum-Tarski quotient algebra is an orthoimplication algebra which generalizes the author's implication algebra. The associated order structure is a semi-orthomodular lattice. The theory of orthomodular lattices is obtained by adjoining a falsity symbol to the underlying orthologic or a least element to the orthoimplication algebra.

In 2016, the Colorado legislature passed an amendment to Colorado’s medical proxy law that established a process for the appointment of a physician to act as proxy decision maker of last resort for an unrepresented patient (Colorado HB 16-1101: Medical Decisions For Unrepresented Patients). The legislative process brought together a diverse set of stakeholders, not all of whom supported the legislation. Following passage of the statutory amendment, the Colorado Collaborative for Unrepresented Patients (CCUP), a group of advocates responsible for initiating (...) the legislative process, coordinated a unique effort to engage these stakeholders in the creation of a set of voluntary guidelines to assist facilities and individual careproviders in the implementation of policies and procedures enabled by the statute. This article delineates the questions and concerns of stakeholders, describes how those issues were addressed within the guidelines, and proposes additional opportunities for research to assess the impact of the legislation in Colorado. (shrink)

New communication technologies such as the microcomputer, videotex/teletext systems, the videocassette recorder, and satellite receiving dishes have been available to farmers since the early 1980s. This longitudinal study examines ethical issues associated with the impact that differential patterns of adoption and use of these technologies have had on inequalities among farmers from 1982 to 1989. The results demonstrate a strong adoption and use bias toward larger scale farmers who already have well-developed skills for handling information. This bias is especially strong (...) for microcomputer and videotex/teletext systems, and it isincreasing over time. Although the same farmers are not adopting all communication innovations, there is a strong tendency toward the already information-rich making the most use of the innovations they adopt. The article concludes with several recommendations that would help minimize some of these information inequalities. (shrink)

One of the most dominant approaches to semantics for relevant (and many paraconsistent) logics is the Routley-Meyer semantics involving a ternary relation on points. To some (many?), this ternary relation has seemed like a technical trick devoid of an intuitively appealing philosophical story that connects it up with conditionality in general. In this paper, we respond to this worry by providing three different philosophical accounts of the ternary relation that correspond to three conceptions of conditionality. We close by briefly discussing (...) a general conception of conditionality that may unify the three given conceptions. (shrink)

Background: Electroconvulsive therapy is one of the most effective treatments for major depressive disorder. Recently, there has been increasing attention to evaluate the effect of ECT on resting-state functional magnetic resonance imaging. This study aims to compare rs-fMRI of depressive disorder patients with healthy participants, investigate whether pre-ECT dynamic functional network connectivity network estimated from patients rs-fMRI is associated with an eventual ECT outcome, and explore the effect of ECT on brain network states.Method: Resting-state functional magnetic resonance imaging data were (...) collected from 119 patients with depression or depressive disorder, and 61 healthy participants, with an age mean of 52.25 years old. The pre-ECT and post-ECT Hamilton Depression Rating Scale were 25.59 ± 6.14 and 11.48 ± 9.07, respectively. Twenty-four independent components from default mode and cognitive control network were extracted, using group-independent component analysis from pre-ECT and post-ECT rs-fMRI. Then, the sliding window approach was used to estimate the pre-and post-ECT dFNC of each subject. Next, k-means clustering was separately applied to pre-ECT dFNC and post-ECT dFNC to assess three distinct states from each participant. We calculated the amount of time each subject spends in each state, which is called “occupancy rate” or OCR. Next, we compared OCR values between HC and DEP participants. We also calculated the partial correlation between pre-ECT OCRs and HDRS change while controlling for age, gender, and site. Finally, we evaluated the effectiveness of ECT by comparing pre- and post-ECT OCR of DEP and HC participants.Results: The main findings include depressive disorder patients had significantly lower OCR values than the HC group in state 2, where connectivity between cognitive control network and default mode network was relatively higher than other states, Pre-ECT OCR of state, with more negative connectivity between CCN and DMN components, is linked with the HDRS changes. This means that those DEP patients who spent less time in this state showed more HDRS change, and The post-ECT OCR analysis suggested that ECT increased the amount of time DEP patients spent in state 2.Conclusion: Our finding suggests that dynamic functional network connectivity features, estimated from CCN and DMN, show promise as a predictive biomarker of the ECT outcome of DEP patients. Also, this study identifies a possible underlying mechanism associated with the ECT effect on DEP patients. (shrink)

"Simone Weil's bibliography": p. [181]-194. Includes index. Introduction / George Abbott White -- The jagged edge / Michele Murray -- Simone Weil's mind / Robert Coles -- The life and death of Simone Weil / J.M. Cameron -- Simone Weil, last things / Michele Murray -- Simone Weil's Iliad / Michael K. Ferber -- Notes on Simone Weil's Iliad / Joseph H. Summers -- Patriotism and The need for roots / Conor Cruise O'Brien -- Marxism-Leninism and the language of (...) Politics magazine / Staughton Lynd -- Simone Weil's work experiences / George Abbott White. (shrink)

"In 2003 the Getty Museum, which holds a collection of about 240 Weston prints, hosted a colloquium on the photographer. This volume in the In Focus series records remarks by the author, Brett Abbott, along with those of six other participants: William Clift, Amy Conger, David Featherstone, Weston Naef, David Travis, and Jennifer Watts. Context for their conversation is provided by the author's introduction, plate texts, and chronology. Approximately fifty of Weston's images demonstrate why his work continues to resonate (...) with a contemporary public and serves as a model for a host of photographers active today."--BOOK JACKET. (shrink)

"Accompanies the exhibition Engaged Observers: Documentary Photography since the Sixties, held at the J. Paul Getty Museum, Los Angeles, June 29-November 17, 2010.".

Hypnagogic and hypnopompic experiences (HHEs) accompanying sleep paralysis (SP) are often cited as sources of accounts of supernatural nocturnal assaults and paranormal experiences. Descriptions of such experiences are remarkably consistent across time and cultures and consistent also with known mechanisms of REM states. A three-factor structural model of HHEs based on their relations both to cultural narratives and REM neurophysiology is developed and tested with several large samples. One factor, labeled Intruder, consisting of sensed presence, fear, and auditory and visual (...) hallucinations, is conjectured to originate in a hypervigilant state initiated in the midbrain. Another factor, Incubus, comprising pressure on the chest, breathing difficulties, and pain, is attributed to effects of hyperpolarization of motoneurons on perceptions of respiration. These two factors have in common an implied alien ''other'' consistent with occult narratives identified in numerous contemporary and historical cultures. A third factor, labeled Unusual Bodily Experiences, consisting of floating/flying sensations, out-of-body experiences, and feelings of bliss, is related to physically impossible experiences generated by conflicts of endogenous and exogenous activation related to body position, orientation, and movement. Implications of this last factor for understanding of orientational primacy in self-consciousness are considered. Central features of the model developed here are consistent with recent work on hallucinations associated with hypnosis and schizophrenia. (shrink)

Read thus the simile presents nothing eccentric. In ver. 101 Hosius and Lejay read male separat, which not only common sense requires but codd. VUQ authorize: not so Mr. Haskins, who follows a multitude of codd. in offering mare separat. But a slight further correction is necessary: to read Aegaeon in 103 for the MS. Aegeo, ‘Withdraw the land, and Aegaean would smash Ionian Sea.’ Those who make Isthmos the subject of frangat cite Stat. Silu. IV. iii. 59.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Eric Doyle OFM: Hidden Architect of the Retrieval of the Franciscan Charism by Brenda AbbottRobert J. Karris, OFMBrenda Abbott, Eric Doyle OFM: Hidden Architect of the Retrieval of the Franciscan Charism. Durham, UK: Franciscan Publishing, 2021. Pp. vii + 388. 16 photos. £15.00. ISBN: 9781915198013.Father Eric Doyle, OFM, a member of the Province of the Immaculate Conception, UK, was born in 1938 and died in 1984. He (...) was highly talented and educated, steeped in the Franciscan tradition, a superb and humorous communicator. He was just right for his time, he was ahead of his time, and he may be just what Franciscans need today in their time as they continue to renew themselves in the spirit of St. Francis and in Franciscan Christology and spirituality.Abbott sets down her goal: "My purpose and goal in publishing this book is that something of the man and his vision will be communicated here, and that a new generation of Franciscan friars and scholars, as well as believers and unbelievers more widely, may be inspired by this vision and become aware of Doyle's enduring and precious legacy" (ii). She accomplishes her goal through an introduction, fifteen chapters which mainly delve into Doyle's Franciscan Christology and spirituality, and a conclusion. Endnotes follow each chapter. The book, which is very well-researched and written, ends with two appendices and a bibliography. Abbot has marvelously achieved her goal.The introduction is followed by: chapter 1, "Early Life: 1938–1970"; chapter 2, "The Friar"; chapter 3, "The Teacher"; chapter 4, "The Shepherd and Evangeliser"; chapter 5, "The Scholar"; chapter 6, "The Mystic"; chapter 7, "The Franciscan Theologian (Part 1)"; chapter 8, "The Franciscan Theologian (Part 2)"; chapter 9, "The Franciscan Theologian (Part 3)"; chapter 10, "The Franciscan Theologian (Part 4)"; chapter 11, "The Ecologist: Our Sister Mother Earth"; chapter 12, "The Ecumenist: Our Brothers and Sisters in Christ"; chapter 13, "The Post–Vatican II Theologian"; chapter 14, "The Prophet: A Franciscan Legacy (Part 1)"; and chapter 15, "The Prophet: A Franciscan Legacy (Part 2)."In the space allotted me, I provide three snapshots of Eric Doyle. First is the assessment of Doyle from an outside source, Bishop Thomas McMahon, who in his eulogy said: "He put profound truths in a very [End Page 249] simple way and conveyed always a sense of the numinous. … [He was] vivid, articulate, deeply learned, intensely human, hugely alive, full of mischief, unsparing of self … a contemporary Francis. His Franciscan spirituality permeated his total thinking" (174). I underscore Bishop Mc-Mahon's emphasis on St. Francis and his spirituality. I see implied here Doyle's teaching about the Absolute Primacy of Christ—that Christ is head of all creation and conqueror of sin and death, and that the reason for Christ's incarnation is not sin but love—demonstrating Doyle's retrieval of the best from the Franciscan tradition.The second snapshot points to two areas where Doyle was ahead of his time. First, he was a TV personality. Abbott dedicates pages 117–23 to Doyle as a wonderful TV presence. From 1971 to 1984 he was on four hundred programs of The Big Question. One reviewer noted: "The length, breadth and width of his discourse … is colossal … This man is an original, a non-pareil; before they made him, they broke the mould" (121). Second, in his book on Francis's Canticle of Brother Sun, first published in 1980, Doyle anticipated many of Pope Francis' teachings in Laudato Si'. As Abbott says: "Foreshadowing much of Pope Francis' encyclical Laudato Si', Doyle demonstrates how belief in the universal brotherhood and sisterhood of creation can help us create a better world" (270).The third snapshot is an indication of how Doyle's legacy continues in print. Doyle's St Francis and the Song of Brotherhood has been reprinted a number of times, most recently in 1997 by Franciscan Institute Publications as St. Francis and the Song of Brotherhood and Sisterhood. It has been translated into five languages: Italian, German, Portuguese, Korean, and Japanese. Under the imprint of Tau Publications is My Heart's Quest: Collected Writings of Eric Doyle, Friar Minor, Theologian, edited by Josef Raischl... (shrink)

The high moral tone of Horace's Reguhls ode makes it unsurprising that the poet should employ the traditional imagery of philosophers, both in the speech of Regulus and in the final simile. I should like here to point out some instances which seem to have escaped the notice of commentators.This passage is intended to illustrate the lost ‘virtus’ of the prisoners in Carthage, who, Regulus claims, will be of no greater use to the Romans if ransomed since they were cowardly (...) enough to surrender in the first place. For the first image of dyeing wool Kiessling–Heinze refer the reader to Lucretius 6.1074–7:purpureusque colos conchyli iungitur unacorpore cum lanae, dirimi qui non queat usquam,non si Neptuni fluctu renovare operam des,non mare si totum velit eluere omnibus undis.This gives the first hint that the image belongs to the philosophical tradition, though it does not seem to occur in the extant remains of Epicurus. This is confirmed by a passage of Plato, who at Rep. 429d ff. has an elaborate image taken from the dyer's art. The Guardians of the ideal city are to be carefully selected and prepared like wool for the dyeing process of education; then, as good wool keeps its colour after dyeing, so the Guardians will keep right opinions when they are taught them. The image is summarized by Socrates at 430a ff. (shrink)

Nineteen obituaries of recently deceased Fellows of the British Academy: W S Allen; George Anderson; A C de la Mare; John Flemming; James Harris; John Hurst; Casimir Lewy; Donald MacDougall; Colin Matthew; Edward Miller; Michio Morishima; Brian Reddaway; Marjorie Reeves; C Martin Robertson; Conrad Russell, and Arnold Taylor.

Although histories of cognitive behaviour therapy have begun to appear, their use with people with psychosis diagnoses has received relatively little attention. In this article, we elucidate the conditions of possibility for the emergence of cognitive behaviour therapy for psychosis (CBTp) in England between 1982 and 2002. We present an analysis of policy documents, research publications and books, participant observation, and interviews with a group of leading researchers and senior policy actors. Informed by Derksen and Beaulieu’s articulation of social technologies, (...) we show how CBTp was developed and stabilised through the work of a variety of overlapping informal, academic, clinical, professional, and policy networks. The profession of clinical psychology played a key role in this development, successfully challenging the traditional ‘division of labour’ where psychologists focused on ‘neurosis’ and left ‘psychosis’ to psychiatry. Following Abbott's systems approach to professions, we identify a number of historical factors that created a jurisdictional vulnerability for psychiatry while strengthening the jurisdictional legitimacy of clinical psychology in providing psychological therapies to service users with psychosis diagnoses. The National Institute for Health and Clinical Excellence played a significant role in adjudicating jurisdictional legitimacy, and its 2002 schizophrenia guidelines, recommending the use of psychological therapies, marked a radical departure from the psychiatric consensus. Our analysis may be of wider interest in its focus on social technologies in a context of jurisdictional contestation. We discuss the implications of our study for the field of mental health and for the relationship between clinical psychology and psychiatry. (shrink)

Progressive intellectuals at the turn of the last century founded the modern American university, created its disciplines and edited the journals that codified their thoughts. They created the ligaments of the national administrative and regulatory state; they helped legitimate the creation of a national financial and industrial corporate economy. Through the writings of Lyman Abbott, Albion Small, and Simon Patten, three features of progressive thought are underlined: the primacy of a narrative, their hostility to “principled” or abstract-philosophical forms of (...) political and social thought, and their confidence that historical modes of social inquiry would produce “laws”? of progress that would guide practice and anchor values integrating self and society on a democratic basis. Five topics contain these animating features: national patriotism, the new industrial economy, a new democratic ethic, social Christianity, and their critique of the dominance of constitutional jurisprudence and law in American political institutions and practices. (shrink)